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1. Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie

   2007 - Prion infectivity and its molecular marker, the pathological prion protein PrP(Sc), accumulate in the central nervous system and often also in lymphoid tissue of animals or humans affected by …

2. Prevention Reporting and Data Sources – Proceedings of the National and Federal State Level Workshop of German Federal Health Reporting – JoHM S2/2018

   May 16, 2018 - The Robert Koch Institute (RKI) and the Federal Centre for Health Education (BZgA) organised a two-day workshop together with representatives from health reporting at the federal state level. The …

3. Susceptibility of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) to chlorhexidine digluconate, octenidine dihydrochloride, polyhexanide, PVP-iodine and triclosan in comparison to hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA): a standardized comparison.

4. Abstracts: The German Health Interview and Examination Survey for Adults – Results of the first wave (DEGS1)

   May 28, 2013 - Abstracts: The German Health Interview and Examination Survey for Adults – Results of the first wave (DEGS1)

5. Decontamination of surgical instruments from prion proteins: in vitro studies on the detachment, destabilization and degradation of PrPSc bound to steel surfaces

   2004 - Effective reprocessing of surgical instruments ensuring elimination of inadvertent contamination with infectious agents causing transmissible spongiform encephalopathies (TSEs) is essential for the …

6. Discriminating scrapie and BSE isolates by infrared spectroscopy of pathological prion protein

   2004 - For the surveillance of transmissible spongiform encephalopathies (TSEs) in animals and humans, the discrimination of different TSE strains causing scrapie, BSE, or Creutzfeldt-Jakob disease …

7. Preclinical deposition of pathological prion protein PrPSc in muscles of hamsters orally exposed to scrapie

   2004 - Recently, pathological prion protein PrP(Sc), the putative key constituent of infectious agents causing transmissible spongiform encephalopathies (TSEs), was found in muscles of rodents experimentally …

8. Autocatalytic self-propagation of misfolded prion protein

   2004 - Prions are thought to replicate in an autocatalytic process that converts cellular prion protein (PrP(C)) to the disease-associated misfolded PrP isoform (PrP(Sc)). Our study scrutinizes this …

9. The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of alpha-linked polyglucose

   2005 - An inert polysaccharide scaffold identified as a 5–15% component of prion rods (PrP 27–30) is unambiguously distinguishable from the N-glycosyl groups and the GPI anchor of PrP, and consists …

10. Gel free analysis of the proteome of intracellular Leishmania mexicana

    2010 - Investigating the proteome of intracellular Leishmania amastigotes has recently become possible due to the exploitation of fluorescence activated intracellular parasite sorting. Here, we employed this …

11. Direct visualization of peptide/MHC complexes at the surface and in the intracellular compartments of cells infected in vivo by Leishmania major

    2010 - Protozoa and bacteria infect various types of phagocytic cells including macrophages, monocytes, dendritic cells and eosinophils. However, it is not clear which of these cells process and present …

12. Pathological prion protein in muscles of hamsters and mice infected with rodent-adapted BSE or vCJD

    2006 - Recently, pathological prion protein (PrPTSE) was detected in muscle from sheep infected with scrapie, the archetype of transmissible spongiform encephalopathies (TSEs). This finding has highlighted …

13. Carriage of extended-spectrum beta-lactamase-plasmids does not reduce fitness but enhances virulence in some strains of pandemic E. coli lineages

14. Acid inactivation of prions: efficient at elevated temperature or high acid concentration

    2006 - Scrapie prion rods isolated from hamster and non-infectious aggregates of the corresponding recombinant protein rPrP(90–231) were incubated with hydrochloric acid. The amount of PrP and of infectivity …

15. Detection of prion particles in samples of BSE and scrapie by fluorescence correlation spectroscopy without proteinase K digestion

    2006 - A characteristic feature of prion diseases such as bovine spongiform encephalopathy (BSE) is the accumulation of a pathological isoform of the host-encoded prion protein, PrP. In contrast to its …

16. FTIR-microspectroscopy of prion-infected nervous tissue

    2006 - The family of transmissible spongiform encephalopathies (TSE), also termed prion diseases, is a group of fatal, neurodegenerative diseases characterized by the accumulation of a misfolded protein, the …

17. Structural differences between TSEs strains investigated by FT-IR spectroscopy

    2006 - Strain diversity in transmissible spongiform encephalopathies (TSEs) has been suggested to be “enciphered” in the structure of the misfolded prion protein isoform PrPSc. We have recently demonstrated …

18. emergency department weekly report (30.3.2022)

    March 30, 2022 - The Emergency Department Situation Report presents data from the routine documentation of selected emergency departments in Germany, and shows the current emergency department utilisation.

19. Zur Beherrschbarkeit von Infektionsrisiken - Primum non nocere - Anmerkungen unter Berücksichtigung von Hygienestandards im Arzthaftungsrecht.

    2009 - Die Frage nach der "Beherrschbarkeit von Infektionsrisiken" kommt häufig genug leider erst dann auf, wenn ein Arzt oder eine medizinische Einrichtung mit dem Vorwurf konfrontiert werden, schuldhaft …

20. Nicht pharmazeutische Maßnahmen der Infektionsprävention

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