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1. Regelungen für die Beförderung ansteckungsgefährlicher Stoffe. (Online Ergänzung zu Caspari G [2012]: Kap. 6.9 Laboratorien mit Infektionsrisiken. S. 484–490)

2. Fatal anthrax infection in a heroin user from southern Germany, June 2012

3. Wie krank machen unsere Krankenhäuser? Neues Infektionsschutzgesetz im August in Kraft getreten

4. Nosokomiale Infektionen. (Online Ergänzung zu Mielke M [2012]: Kap.10.1 Prävention nosokomialer Infektionen – rechtliche Verankerung und nationale Standards, S. 623–628)

5. A novel mechanism of growth phase-dependent tolerance to isoniazid in mycobacteria.

   2012 - Background: The mechanism underlying mycobacterial phenotypic tolerance to isoniazid is unknown. Results: MDP1, a mycobacterial histone-like protein, down-regulates KatG expression. Conclusion: …

6. Mycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, 'Dormancy Associated Translation Inhibitor (DATIN)'.

   2012 - Mycobacterium tuberculosis is a major human pathogen that has evolved survival mechanisms to persist in an immune-competent host under a dormant condition. The regulation of M. tuberculosis metabolism …

7. Architecturally the same, but playing a different game: The diverse species-specific roles of DivIVA proteins

   2012 - News and Views to: S Halbedel, B Hahn, RA Daniel, A Flieger. DivIVA affects secretion of virulence-related autolysins in Listeria monocytogenes. Mol Microbiol 2012; 83: 821-839 PMID: 22353466 DOI: …

8. Kap. 2.9 Aufbereitung von Medizinprodukten

9. Toward rubella elimination in Europe: an epidemiological assessment

   2012 - Background The elimination of rubella and prevention of congenital rubella syndrome (CRS) by 2015 are established goals for Europe. Our aim was to review the epidemiology of rubella in relation to …

10. A GFP-labeled monitoring tool to quantify conjugative plasmid transfer between Gram-positive and Gram-negative bacteria

    2012 - On basis of pIP501 a GFP-tagged monitoring tool was constructed for quantifying plasmid mobilization among Gram-positive bacteria and between Gram-positive Enterococcus faecalis and Gram-negative E. …

11. Increase in malaria cases imported from Pakistan to Germany in 2012

12. Injektionsmilzbrand – neu aufgetretene Fälle bei Heroinabhängigen

    2012 - Hintergrund: Injektionsmilzbrand ist eine seltene Erkrankung bei Heroinkonsumierenden und wird durch Bacillus anthracis verursacht. Im Jahr 2012 sind vier Fälle in Deutschland aufgetreten, wovon ein …

13. Impact of HIV-1 subtype on CD4 count at HIV seroconversion, rate of decline and viral load set point in European seroconverter cohorts

    2012 - Background: Whether HIV-1 subtype influences disease progression remains unclear. We compared CD4 levels at seroconversion, rates of decline and viral load set-point in individuals infected with …

14. Generation and characterization of a Cowpox virus mutant lacking host range factor CP77

    2012 - Cowpox virus (CPXV) host range factor CP77 was identified to be required for virus replication in Chinese hamster ovary (CHO) cells, but the underlying molecular mechanism by which CP77 modulates host …

15. In vitro Activity of Tigecycline and Molecular Characterization of Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates from a University Hospital in South-Western Germany

    2012 - Background: Extended-spectrum β-lactamase (ESBL)-producing organisms are spreading worldwide in hospital and community settings. Methods: A total of 328 unduplicated ESBL-producing Enterobacteriaceae …

16. Genome Diversity and Host Interaction of Noroviruses. Chapter 12

17. Host-Driven Plasticity of the Human Immunodeficiency Virus Genome. Chapter 9

18. Influenza A viruses target type II pneumocytes in the human lung

    2012 - Background. Highly pathogenic avian H5N1 influenza viruses preferentially infect alveolar type II pneumocytes in human lung. However, it is unknown whether this cellular tropism contributes to high …

19. Need for long-term follow-up in enterohemorrhagic Escherichia coli-associated hemolytic uremic syndrome due to late-emerging sequelae

    2012 - Background.  The aim of this study was to evaluate the long-term prognosis of children with hemolytic uremic syndrome (HUS). Methods.  Over a 6-year period, 619 pediatric patients with the clinical …

20. Illegitimate recombination: An efficient method for random mutagenesis in Mycobacterium avium subsp. hominissuis.

    2012 - Background The genus Mycobacterium (M.) comprises highly pathogenic bacteria such as M. tuberculosis as well as environmental opportunistic bacteria called non-tuberculous mycobacteria (NTM). While …

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