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1. Sharing More than Friendship - Nasal Colonization with Coagulase-Positive Staphylococci (CPS) and Co-Habitation Aspects of Dogs and Their Owners

   2012 - Background Since the relationship between dogs and their owners has changed, and dogs moved from being working dogs to family members in post-industrial countries, we hypothesized that zoonotic …

2. Confidence-based Somatic Mutation Evaluation and Prioritization

   2012 - Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, …

3. Long-term effects of PERV-specific RNA interference in transgenic pigs

   2012 - Background: Porcine endogenous retroviruses (PERVs) represent a risk of xenotransplantation using porcine cells, tissues, or organs, as they are integrated in the porcine genome and have been shown to …

4. Terminology

5. In Vitro Antimicrobial Effect of a Cold Plasma Jet against Enterococcus faecalis Biofilms

   2012 - The hypothesis that a cold plasma jet has the antimicrobial effect against Enterococcus faecalis biofilms was tested in vitro. 27 hydroxyapatite discs were incubated with E. faecalis for six days to …

6. Origin of Human T-Lymphotropic Virus Type 1 in Rural Côte d’Ivoire

   2012 - Simian T-lymphotropic virus type 1 (STLV-1) strains occasionally infect humans. However, the frequency of such infections is unknown. We show that direct transmission of STLV-1 from nonhuman primates …

7. Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1

   2012 - BACKGROUND The mechanism by which HIV-1 induces AIDS is still unknown. Previously, synthetic peptides corresponding to the conserved immunosuppressive (isu) domain in gp41 of HIV-1 had been shown to …

8. Biological and phylogenetic characteristics of Yellow Fever virus lineages from West Africa

   2012 - The Yellow Fever Virus (YFV) – the first proven human pathogenic virus – although isolated in 1927, is still a major public health problem especially in West Africa where it causes outbreaks every …

9. Very low birth weight infants after discharge: What do parents describe?

   2012 - Background Morbidity and mortality in Very Low Birth Weight (VLBW) infants during their hospital stay have been well described. However, there are insufficient data regarding health problems after …

10. MSH2 and CXCR4 involvement in malignant VIPoma

    2012 - Background Vasoactive intestinal polypeptide secreting tumors(VIPomas) are rare endocrine tumors of the pancreas with an estimated incidence of 0.1 per million per year. The molecular mechanisms that …

11. HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity

    2012 - DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal …

12. Pegylated interferon-based treatment in patients with advanced liver disease due to chronic delta hepatitis

    2012 - Background/aims: The safety and efficacy of interferons in advanced delta hepatitis have not been explored. The aim of this subanalysis of a multicenter clinical trial was to compare the efficacy and …

13. Treponema pallidum infection in the wild baboons of East Africa: Distribution and genetic characterization of the strains responsible

    2012 - It has been known for decades that wild baboons are naturally infected with Treponema pallidum, the bacterium that causes the diseases syphilis (subsp. pallidum), yaws (subsp. pertenue), and bejel …

14. Detection of antibodies to Campylobacter in humans using enzyme-linked immunosorbent assays: a review of the literature

    2012 - Campylobacteriosis is the most common cause of bacterial foodborne illness in the European Union and the United States. Infection with Campylobacter spp. is frequently associated with different …

15. Comparison of real-time PCR and MassTag PCR for the multiplex detection of highly pathogenic agents

    2012 - Multiplex PCR assays are a cost- as well as labour-effective way to analyse one sample for several pathogens simultaneously. Besides the mutual competition of the individual PCR reactions included in …

16. Gesundheitliche Ungleichheit im Jugendalter - Welche Bedeutung kommt der Schulbildung zu?

17. Comparison of Staphylococcus aureus isolates associated with food intoxication with isolates from human nasal carriers and human infections

    2012 - Staphylococcus aureus represents an organism of striking versatility. While asymptomatic nasal colonization is widespread, it can also cause serious infections, toxinoses and life-threatening …

18. Multimorbidität als Interventionsherausforderung

19. Cowpox virus but not Vaccinia virus induces secretion of CXCL1, IL-8 and IL-6 and chemotaxis of monocytes in vitro

    2012 - Orthopoxviruses are large DNA viruses which can cause disease in numerous host species. Today, after eradication of Variola virus and the end of vaccination against smallpox, zoonotic Orthopoxvirus …

20. Viral evolution in chronic hepatitis B: a branched way to HBeAg seroconversion and disease progression?

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