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1. From types to trees: Reconstructing the spatial spread of staphylococcus aureus based on DNA variation

   2011 - Tracing the spatial spread of pathogens is a key objective of molecular infectious disease epidemiology. Accordingly, a wide range of genotyping approaches have been used to monitor the dissemination …

2. Calculation of direct antiretroviral treatment costs and potential cost savings by using generics in the German HIV ClinSurv Cohort

   2011 - Background/Aim of the Study The study aimed to determine the cost impacts of antiretroviral drugs by analysing a long-term follow-up of direct costs for combined antiretroviral therapy, cART,-regimens …

3. Growth of influenza A virus is not impeded by simultaneous removal of the cholesterol binding and acylation sites in the M2 protein

   2011 - Influenza virus assembly and budding occur in the 'budozone', a coalesced raft domain in the plasma membrane. The viral transmembrane protein M2 is implicated in virus particle scission, the ultimate …

4. No Detection of XMRV in Blood Samples and Tissue Sections from Prostate Cancer Patients in Northern Europe

   2011 - Background We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The …

5. Influenza B virus with modified hemagglutinin cleavage site as a novel attenuated live vaccine

   2011 - Background. Both pandemic and interpandemic influenza is associated with high morbidity and mortality worldwide. Seasonal epidemics are caused by both influenza A and B virus strains that cocirculate …

6. Recent outbreak of hemolytic uremic syndrome in Germany

7. Second external quality assessment of the molecular diagnostic of West Nile virus: Are there improvements towards the detection of WNV?

   2011 - Background WNV epidemics occur worldwide, new WNV isolates were isolated in southern-east Europe belonging to WNV lineage 2. A first international proficiency study on WNV indicted that some …

8. Humane pluripotente Stammzellen – Perspektiven ihrer Nutzung und die Forschungssituation in Deutschland

9. Chromosomal Rearrangements in Salmonella enterica Serovar Typhi Strains Isolated from Asymptomatic Human Carriers

   2011 - Host-specific serovars of Salmonella enterica often have large-scale chromosomal rearrangements that occur by recombination between rrn operons. Two hypotheses have been proposed to explain these …

10. Anforderungen an die Hygiene bei Punktionen und Injektionen. Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut (RKI).

    2011 - Die im nachfolgenden Dokument gegebenen Empfehlungen basieren auf den aktuellen Kategorien der Richtlinie für Krankenhaushygiene und Infektionsprävention aus dem Jahr 2010.

11. The surface topography of the choroid plexus. Environmental, low and high vacuum scanning electron microscopy

    2011 - Environmental scanning electron microscopy (ESEM) allows the examination of hydrated and dried specimens without a conductive metal coating which could be advantageous in the imaging of biological and …

12. A space–time conditional intensity model for invasive meningococcal disease occurrence

    2011 - A novel point process model continuous in space–time is proposed for quantifying the transmission dynamics of the two most common meningococcal antigenic sequence types observed in Germany 2002–2008. …

13. Optimisation of expression and purification of the feline and primate foamy virus transmembrane envelope proteins using a 96 deep well screen

    2011 - The production of recombinant transmembrane proteins is due to their biochemical properties often troublesome and time consuming. Here the prokaryotic expression and purification of the transmembrane …

14. Molecular and infectivity studies of porcine circovirus in vaccines

    2011 - This report describes FDA's laboratory response to the 2010 reports that porcine circovirus type 1 (PCV-1) DNA was present in U.S.-licensed rotavirus vaccines and in cells used to produce inactivated …

15. DART – gemeinsam Antibiotikaresistenzen verhüten und bekämpfen. Deutsche Antibiotika-Resistenzstrategie – eine Zwischenbilanz des RKI

16. Origin of XMRV and its demise as a human pathogen associated with Chronic Fatigue Syndrome

    2011 - Retroviruses are well known pathogens of mammals, birds and fish. Their potential to induce cancer in chickens was already described almost 100 years ago and murine retroviruses have been a subject of …

17. Special Issue: World tuberculosis day 2011

    2011 - This special issue discusses the following topics: marking 15 years of efforts towards a comprehensive European TB surveillance system - the epidemiological situation of TB in the EU/EEA in 2009; …

18. Diversity of Salmonella enterica serovar Derby isolated from pig, pork and humans in Germany

    2011 - Salmonella enterica serovar Derby (S. Derby) is one of the most prevalent serovars in pigs in Europe and in the U.S. and ranks among the 10 most frequently isolated serovars in humans. Therefore, a …

19. Imaging and strain analysis of nano-scale SiGe structures by tip-enhanced raman spectroscopy

    2011 - The spatial resolution and high sensitivity of tip-enhanced Raman spectroscopy allows the characterization of surface features on a nano-scale. This technique is used to visualize silicon-based …

20. Assessment of varicella vaccine effectiveness in Germany: a time-series approach

    2011 - A multivariate time-series regression model was developed in order to describe the 2005–2008 age-specific time-course of varicella sentinel surveillance data following the introduction of a varicella …

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