Search results

1. Minor drug-resistant HIV type-1 variants in breast milk and plasma of HIV type-1-infected Ugandan women after nevirapine single-dose prophylaxis

   2011 - Background: Nevirapine single-dose (NVP-SD) reduces mother-to-child transmission of HIV type-1 (HIV-1), but frequently induces resistance mutations in the HIV-1 genome. Little is known about …

2. Microbial biofilms on the surface of intravaginal rings worn in non-human primates

   2011 - Millions of intravaginal rings (IVRs) are used by women worldwide for contraception and for the treatment of vaginal atrophy. These devices also are suitable for local and systemic sustained release …

3. Protocol and methodology of the Stroke in Young Fabry Patients (sifap1) study: a prospective multicenter European study of 5,024 young stroke patients aged 18–55 years

   2011 - Background: Stroke in the young has not been thoroughly investigated with most previous studies based on a small number of patients from single centers. Furthermore, recent reports indicate that Fabry …

4. Analgesic use in a national community sample of German children and adolescents

   2011 - Background: Previous studies suggest that pain management by analgesic medications may be low among children. This study aims to investigate analgesic use and its correlates among children in Germany. …

5. Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study

   2011 - Background The effect of transmitted drug resistance (TDR) on first-line combination antiretroviral therapy (cART) for HIV-1 needs further study to inform choice of optimum drug regimens. We …

6. Dengue in Thailand and Cambodia: An Assessment of the Degree of Underrecognized Disease Burden Based on Reported Cases

   2011 - Background Disease incidence data are needed to guide decision-making for public health interventions. Although dengue is a reportable disease in Thailand and Cambodia, the degree that reported …

7. Host range of enterococcal vanA plasmids among Gram-positive, intestinal bacteria

   2011 - Objectives The most prevalent type of acquired glycopeptide resistance is encoded by the vanA transposon Tn1546 located mainly on transferable plasmids in Enterococcus faecium. The limited occurrence …

8. Monitoring pandemic influenza A(H1N1) vaccination coverage in Germany 2009/10 - Results from thirteen consecutive cross-sectional surveys

   2011 - To monitor pandemic influenza A(H1N1) vaccine uptake during the vaccination campaign in Germany 2009/10, thirteen consecutive cross-sectional telephone-surveys were performed between November 2009 and …

9. Hepatitis E - Häufiger eine autochthone als eine importierte Erkrankung

   2011 - Hepatitis E ist eine seltene, seit 2001 in Deutschland meldepflichtige Erkrankung. Seither wurden jedes Jahr zwischen 11 und 62 importierte Hepatitis-E-Virus-(HEV) Infektionen übermittelt. Von diesen …

10. Watch out for the even eviler cousin – sorbitol-fermenting E. coli O157

11. Enhanced surveillance during a large outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany, May to June 2011

    2011 - Germany has a well established broad statutory surveillance system for infectious diseases. In the context of the current outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga …

12. The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

    2011 - Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and sepsis. Pneumococci can be divided into >90 serotypes that show differences in the pathogenicity and invasiveness. We tested …

13. BMI-Selbstauskünfte – Überprüfung der Praktikabilität einer Korrekturformel an einer Stichprobe elf- bis 13-jähriger Mädchen. [Self-assessment of BMI data. Verification of the practicability of a correction formula on a sample of 11- to 13-year-old girls].

    2011 - Die Entscheidung zwischen Messung und Erfragung von Größe und Gewicht zur Errechnung des Body-Mass-Index (BMI) hat Einfluss auf die Ökonomie und Validität dieser Messungen. So sind Selbstauskünfte …

14. Standardization of hepatitis E virus (HEV) nucleic acid amplification technique-based assays: an initial study to evaluate a panel of HEV strains and investigate laboratory performance

    2011 - The performance of hepatitis E virus (HEV) RNA nucleic acid amplification (NAT)-based assays has been investigated using a panel of HEV-containing plasma samples. The panel comprised 22 HEV-positive …

15. Present state and future perspectives of using pluripotent stem cells in toxicology research

    2011 - The use of novel drugs and chemicals requires reliable data on their potential toxic effects on humans. Current test systems are mainly based on animals or in vitro-cultured animal-derived cells and …

16. Functional dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica

    2011 - Salmonella enterica deploys the giant non-fimbrial adhesin SiiE to adhere to the apical side of polarized epithelial cells. The establishment of close contact is a prerequisite for subsequent invasion …

17. Comparison of Staphylococcus aureus isolates associated with food intoxication with isolates from human nasal carriers and human infections

    2011 - Staphylococcus aureus represents an organism of striking versatility. While asymptomatic nasal colonization is widespread, it can also cause serious infections, toxinoses and life-threatening …

18. Comparison of direct cultivation on a selective solid medium, polymerase chain reaction from an enrichment broth, and the BD GeneOhm™ VanR Assay for identification of vancomycin-resistant enterococci in screening specimens

    2011 - Fast and reliable diagnostics of vancomycin-resistant enterococci (VRE) is an important prerequisite for containing VRE transmission rates and controlling VRE outbreaks among hospital patients. The BD …

19. Peginterferon plus adefovir versus either drug alone for hepatitis delta

    2011 - BACKGROUND: Chronic infection with hepatitis B virus and hepatitis delta virus (HDV) results in the most severe form of viral hepatitis. There is no currently approved treatment. We investigated the …

20. Epidemiologie der Tuberkulose – Aktuelle Situation in Deutschland und weltweit

    2011 - Auch im 21. Jahrhundert gehört die Tuberkulose (TB) noch zu den weltweit häufigsten Infektionskrankheiten. Nach den Schätzungen der Weltgesundheitsorganisation (WHO) erkrankten im Jahr 2008 mehr als …

Search results 5,121 to 5,140 from a total of 13,838