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1. Potenzieller Nutzen von drei derzeit verfügbaren Pneumokokkenimpfstoffen für Kinder - eine populationsbezogene Erhebung

   2011 - Hintergrund: In Deutschland stehen derzeit 3 Pneumokokkenimpfstoffe zur Verfügung. Ziel dieser Arbeit ist es, den gegenwärtigen Nutzen dieser Impfstoffe anhand von epidemiologischen Daten zu …

2. Application of new assays for rapid confirmation and genotyping of isolates of Rubella virus

   2011 - Rubella virus (RV) isolation is recommended by the WHO Measles and Rubella Labnet for studying the etiology and epidemiology of rubella. However, the absence of cytopathologic effects (CPE) in many of …

3. Chip-calorimetric evaluation of the efficacy of antibiotics and bacteriophages against bacteria on a minute-timescale

   2011 - Rapid detection of antibiotic resistances of clinical bacterial strains would allow an early selective antibiotic therapy and a faster intervention and implementation of infection control …

4. Rauchen – Aktuelle Entwicklungen bei Erwachsenen

5. RNA helicase retinoic acid-inducible gene I (RIG-I) as a sensor of Hantaan virus (HTNV) replication

   2011 - Hantaan virus (HTNV) causes severe human disease. The HTNV genome consists of three ssRNA segments of negative polarity which are complexed with viral nucleocapsid (N) protein. How the human innate …

6. Legionella pneumophila induced IκBζ-dependent expression of il-6 in lung epithelium

   2011 - Legionella pneumophila causes severe community- and hospital-acquired pneumonia. Lung airway and alveolar epithelial cells comprise an important sentinel system in airborne infections. Although …

7. Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly

   2011 - Background The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of …

8. Gestational weight gain and overweight in children: Results from the cross-sectional German KiGGS study

   2011 - Objective. Gestational weight gain (GWG) has been associated with overweight in offspring. The aim of the study was to assess the association of GWG with childhood overweight and a potential effect …

9. Livestock-associated methicillin-resistant Staphylococcus aureus in humans, Europe

   2011 - To estimate the proportion of methicillin-resistant Staphylococcus aureus (MRSA) isolates from humans that were sequence type (ST) 398, we surveyed 24 laboratories in 17 countries in Europe in 2007. …

10. A national cross-sectional study on socio-behavioural factors that influence physicians' decisions to begin antimicrobial therapy

    2011 - Purpose   Current efforts to prevent antimicrobial resistance include limiting antimicrobial use, providing education about appropriate use, and developing better point-of-care tests, but what do …

11. The Hepatitis C epidemic among HIV-positive men who have sex with men: incidence estimates from 1990 to 2007

    2011 - Background: Outbreaks of acute hepatitis C virus (HCV) infection among HIV-infected men having sex with men (MSM) have been described since 2000. However, phylogenetic analysis suggests that the …

12. Generation and characterisation of monoclonal antibodies against influenza virus A, subtype H5N1

    2011 - The emergence of highly pathogenic avian influenza A virus (HPAIV) subtype H5N1 in 1997 has since resulted in large outbreaks in poultry and in transmission from poultry to humans, mostly in southeast …

13. The IFN-γ-inducible GTPase, irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens

    2011 - Clearance of infection with intracellular pathogens in mice involves interferon-regulated GTPases of the IRG protein family. Experiments with mice genetically deficient in members of this family such …

14. Increased Neutralizing Antibody Response after Simultaneous Immunization with Leucogen and the Feline Leukemia Virus Transmembrane Protein

    2011 - To develop improved vaccination strategies against feline leukemia virus (FeLV), rats were immunized with the transmembrane envelope protein p15E of FeLV alone or in combination with the commercial …

15. LDH-A influences hypoxia-inducible factor 1α (HIF1 α) and is critical for growth of HT29 colon carcinoma cells in vivo

    2011 - Serum lactate dehydrogenase (LDH) is a well-known clinical surrogate parameter. A high activity of LDH is associated with a poor prognosis in different tumor types. Here we demonstrate by a gene …

16. Inhibition of poxvirus spreading by the anti-tumor drug Gefitinib (Iressa™)

    2011 - The threat of smallpox virus as a bioterrorist weapon is raising international concerns again since the anthrax attacks in the USA in 2001. The medical readiness of treating patients suffering from …

17. European Risk Assessment Guidance for Infectious Diseases transmitted on Aircraft – the RAGIDA project

    2011 - In order to assist national public health authorities in the European Union to assess the risks associated with the transmission of infectious agents on board aircrafts, the European Centre for …

18. Intra- and interspecies genomic transfer of the Enterococcus faecalis pathogenicity island

    2011 - Enterococci are the third leading cause of hospital associated infections and have gained increased importance due to their fast adaptation to the clinical environment by acquisition of antibiotic …

19. No evidence for transmission of SIVwrc from western red colobus monkeys (Piliocolobus badius badius) to wild west African chimpanzees (Pan troglodytes verus) despite high exposure through hunting

    2011 - Background Simian Immunodeficiency Viruses (SIVs) are the precursors of Human Immunodeficiency Viruses (HIVs) which have lead to the worldwide HIV/AIDS pandemic. By studying SIVs in wild primates we …

20. Characterization of Escherichia coli Strains Isolated from Diarrhea Patients in Sao Paulo: Identification of Intermediate Virulence Factor Profiles by Multiplex PCR

    2011 - Intestinal pathogenic Escherichia coli is a major causative agent of severe diarrhea. In this study the prevalence of different pathotypes among 702 Brazilian diarrhea E. coli isolates was determined …

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