Search results
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Impfen um jeden Preis? – Impfmüdigkeit in Deutschland. Ein Positionspapier der Deutschen Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM)
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Recombinant outer membrane vesicles to augment antigen-specific live vaccine responses
2009 - Release of outer membrane vesicles is a common feature of Gram negative bacteria. There is growing interest in the use of these vesicles in the development of affordable vaccines. However, to exploit …
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Virus-free Gene Transfer Systems in Somatic Gene Therapy
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Gehirninfektionen nach Beinahe-Ertrinken
2009 - Abszesse des ZNS stellen eine besondere Komplikation nach Beinahe-Ertrinken dar; sie werden in erster Linie durch Pilze der Gattung Pseudallescheria/Scedosporium verursacht. Es ist von einer hohen …
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Detection and quantification of minor HIV-1 variants harbouring K103N and Y181C resistance mutations in subtype A and D isolates by allele-specific real-time PCR
2009 - Nevirapine single-dose, commonly used to prevent the mother-to-child transmission of HIV in developing countries, frequently induces viral resistance. Even mutations which occur only in a minor …
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Transmission of Drug-Resistant HIV-1 Is Stabilizing in Europe
2009 - The SPREAD Programme investigated prospectively the time trend from September 2002 through December 2005 of transmitted drug resistance (TDR) among 2793 patients in 20 European countries and in Israel …
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Surveillance of Transmitted HIV Drug Resistance Across Europe in the Era of Newly Approved Antiretroviral Drugs
2009 - Over the last few years, the prevalence of transmitted HIV-1 drug resistance (TDR) has not risen in the industrialised countries of western Europe. As recently reported by the European surveillance …
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Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach
2009 - BACKGROUND: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion …
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Implications and perspectives for HIV surveillance using a serological method to measure recent HIV infections among newly diagnosed individuals: Results from a pilot study 2005-2007 in Berlin, Germany
2009 - Objectives This cross-sectional study was designed to pilot the analysis of clinical data, knowledge about and attitudes towards HIV/AIDS, and prevention and risk behaviour in persons recently …
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PKCα and ε differentially regulate Legionella pneumophila induced GM-CSF
2009 - Legionella pneumophila is an important causative agent of severe pneumonia in humans. The human alveolar epithelium is an effective barrier for inhaled microorganisms and actively participates in the …
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Reptile-associated Salmonellosis in a Breastfed Infant
2009 - Background: Although salmonellosis is one of the most common childhood illnesses associated with enteric bacteria, breastfed babies do not often get infected with Salmonella. In such cases it is …
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Reptile-associated Salmonellosis in Infants in Germany
2009 - Salmonellosis is an important disease in childhood. Increasing infections caused by meat and raw egg consumption starts in the second year of life. The transmission from reptiles to infants is an …
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Escherichia coli encoding Shiga toxin 2f as an emerging human pathogen
2009 - Escherichia coli harbouring the stx2f gene have been previously reported in pigeons. Here we demonstrate the presence of this allele in human diarrhoeagenic E. coli strains originally classified as …
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Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr
2009 - Methicillin-resistant Staphylococcus aureus clonal lineage ST398 and methicillin-susceptible lineage ST9 strains have their main reservoir in swine but can colonize and cause infections in humans. The …
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Phospholipase PlaB of Legionella pneumophila represents a novel lipase family: protein residues essential for lipolytic activity, substrate specificity, and hemolysis
2009 - Legionella pneumophila possesses several phospholipases capable for host-cell manipulation and lung damage. Recently, we discovered the major cell-associated hemolytic phospholipase A PlaB sharing no …
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A novel large-scale approach for identification of Legionella pneumophila mutants defective for amoeba infection uncovers the bdhA/patD operon as a virulence determinant
2009 - Legionella pneumophila, the causative agent of Legionnaires’ disease, is an intracellular parasite of eukaryotic cells. In the environment, it colonizes amoebae. After inhaled into the human lung, the …
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Salmonella enterica serovar Typhi with CTX-M beta-lactamase, Germany
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Characterisation of porin genes from Mycobacterium fortuitum and their impact on growth.
2009 - Background Highly pathogenic mycobacteria like Mycobacterium tuberculosis are characterised by their slow growth and their ability to reside and multiply in the very hostile phagosomal environment and …
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Surveillance von Infektionskrankheiten auf europäischer Ebene
2009 - Mit der im Jahr 1998 von EU-Parlament und Ministerrat getroffenen Entscheidung zur Etablierung eines EU-weiten Netzwerks zur Überwachung von Infektionskrankheiten wurde die Grundlage für die EUweite …
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Clostridium difficile ribotypes 001, 017, and 027 are associated with lethal C. difficile infection in Hesse, Germany
2009 - From January 2008 to April 2009, 72 cases of severe Clostridium difficile infection were reported from 18 different districts in the state of Hesse, Germany. A total of 41 C. difficile isolates from …
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