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1. BCG priming of dendritic cells enhances T regulatory and Th1 function and suppresses allergen-induced Th2 function in vitro and in vivo

   2009 - Background: The inverse correlation of mycobacterial infection with asthma prevalence and the inhibitory effects of vaccination with Bacille Calmette-Guérin (BCG) on airway hyperreactivity in asthma …

2. Influenza Virus

3. Atherothrombotischer Schlaganfall: Welche Maßnahmen sind in der Primärprävention wirksam?

   2009 - Trotz beachtlicher Fortschritte in der Akuttherapie des ischämischen Schlaganfalls bleibt eine effektive Primärprävention die beste Methode zur Senkung derindividuellen und gesamtgesellschaftlichen …

4. Detection and Characterization of Fimbrial sfp Cluster in Enterohemorrhagic Escherichia coli O165:H25/NM from Humans and Cattle

   2009 - The sfp cluster encoding Sfp fimbriae which is located in the large plasmid of sorbitol-fermenting (SF) enterohemorrhagic Escherichia coli (EHEC) O157 (pSFO157) has been considered a unique …

5. Epidemiology of vertigo, migraine and vestibular migraine

   2009 - Both migraine and vertigo are common in the general population with lifetime prevalences of about 16 % for migraine and 7 % for vertigo. Therefore, a concurrence of the two conditions can be expected …

6. A 17-year-old girl with a black eschar. Cowpox virus infection

7. Ein Bericht über durch Heimtierratten auf Menschen übertragene Kuhpockenvirusinfektion

   2009 - Seit einiger Zeit diagnostiziert das Konsiliarlabor für (humane) Pockenerkrankungen des Robert Koch-Instituts Berlin vermehrt Kuhpockenvirusinfektionen beim Menschen. Als deren Ursache wurde jetzt …

8. Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus

   2009 - The impact of globalization on the emergence and spread of pathogens is an important veterinary and public health issue. Staphylococcus aureus is a notorious human pathogen associated with serious …

9. Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS

   2009 - During evolutionary adaptation in the immune system, host defense is traded off against autoreactivity. Signals through the costimulatory receptor CD28 enable T cells to respond specifically to …

10. Prolongierter Verlauf einer durch Zeckenstich übertragenen ulzeroglandulären Tularämie bei einer 20-jährigen Patientin

    2009 - ANAMNESE UND KLINISCHER BEFUND: Eine 20-jährige Patientin wurde wegen einer anhaltend schmerzhaften Lymphknotenschwellung (LKS) in der rechten Axilla zur infektiologischenAbklärung vorgestellt. Sie …

11. Influenza A virus TRIMs the type I interferon response

    2009 - The virulence of many pathogenic viruses depends on suppression of the innate type I interferon defense. For influenza viruses, a unique strategy has now been unraveled, as the viral nonstructural …

12. Indigenous hepatitis E virus infection of a plasma donor in Germany

    2009 - Background Although Europe is supposed to be non-endemic for Hepatitis E virus (HEV), locally acquired human cases are registered, and a relatively high prevalence for anti-HEV was found in blood …

13. Autophagy induction by trehalose counteracts cellular prion infection

    2009 - Prion diseases are fatal neurodegenerative and infectious disorders for which no therapeutic or prophylactic regimens exist. In search of cellular mechanisms that play a role in prion diseases and …

14. Unsung hero Robert C. Gallo

    2009 - Awarding the Nobel prize in physiology or medicine to Francoise Barré-Sinoussi and Luc Montagnier for the discovery of HIV-1, the causative agent of AIDS, is timely given the harm that the virus …

15. Human embryonic stem cell lines and their use in international research

    2009 - Research in human pluripotent stem cells, including human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC), is one of the most dynamic research fields. Despite the high …

16. Cowpox Virus Infection in Pet Rat Owners - Not Always Immediately Recognized

    2009 - Background: The aim of this article is to make physicians of all specialties aware of the possible variations of clinical course in human cowpox infection. This has been a matter of current interest …

17. Entwicklung und Evaluation der nationalen Gesundheitsziele für Kinder und Jugendliche: Welchen Beitrag leistet der Kinder- und Jugendgesundheitssurvey des Robert Koch-Instituts (KiGGS)?

    2009 - Gesundheitsziele werden zunehmend zu einem Steuerungsinstrument der Gesundheitspolitik im nationalen und internationalen Kontext. Im Projekt gesundheitsziele.de wurden mit Blick auf Kinder und …

18. Survivin minigene DNA vaccination is effective against neuroblastoma

    2009 - The inhibitor of apoptosis protein survivin is highly expressed in neuroblastoma (NB) and survivin-specific T cells were identified in Stage 4 patients. Therefore, we generated a novel survivin …

19. Inhibition of growth of Shiga toxin-producing Escherichia coli by non-pathogenic Escherichia coli

    2009 - During routine quality control testing of diagnostic methods for Shiga toxin-producing Escherichia coli (STEC) using stool samples spiked with STEC, it was observed that the Shiga toxin could not be …

20. Porcine circoviruses--small but powerful

    2009 - When porcine circovirus type 1 (PCV1) was isolated more than 40 years ago as a non-pathogenic contaminant of a porcine kidney cell line, enthusiasm and curiosity kept within reasonable limits. …

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