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1. Cell cycle-independent expression of immediate-early gene 3 results in G1 and G2 arrest in murine cytomegalovirus-infected cells

   2008 - The infectious cycle of human cytomegalovirus (HCMV) is intricately linked to the host's cell cycle. Viral gene expression can be initiated only in G0/G1 phase. Once expressed, the immediate-early …

2. Transmission of drug-resistant HIV-1 in Europe remains limited to single classes

   2008 - Background: The spread of drug-resistant HIV-1 might compromise the future success of current first-line regimens. Objective: To analyse the extent and impact of transmission of drug-resistant HIV-1 …

3. DNA-Austausch über Artgrenzen hinweg – Horizontaler Gentransfer

   2008 - Der Erwerb von Erbsubstanz außerhalb der normalen Erbfolge, horizontaler Gentransfer (HGT) genannt, ist als Phänomen bei Bakterien schon seit mehr als 50 Jahren bekannt. Genomsequenzierungen zeigen, …

4. Occurrence and Genetic Diversity of Bacillus anthracis Strains Isolated in an Active Wool-Cleaning Factory

   2008 - Culturable microorganisms from various samples taken at an active factory performing wool and goat hair cleaning were isolated and analyzed. Bacillus anthracis was found in air filter dust, …

5. Sabotage of antiviral signaling and effectors by influenza viruses

   2008 - Vertebrate cells activate multiple signaling modules upon virus infection to eliminate the invading pathogen and to prevent the establishment of a persistent infection. A major immediate response …

6. Borna disease virus infection in Italian children. A potential risk for the developing brain?

7. Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression

   2008 - The type I interferon (IFN) system is a first line of defense against viral infections. Viruses have developed various mechanisms to counteract this response. So far, the interferon antagonistic …

8. Verbreitung multiresistenter Erreger

   2008 - Multiresistenz gegen Antibiotika entsteht bei Bakterien durch die Aufnahme von mobilen genetischen Elementen, die Resistenzgene tragen, sowie durch Resistenzmutation. Die Ausbreitung der Resistenz …

9. Infektionsepidemiologische Daten von Blutspendern 2006. Bericht des Robert Koch-Instituts zu den Meldungen nach § 22 Transfusionsgesetz

   2008 - Gemäß § 22 Transfusionsgesetz (TFG) melden alle Blut- und Plasmaspendeeinrichtungen in Deutschland ihre infektionsepidemiologischen Daten an das Robert Koch-Institut (RKI). Diese erlauben Aussagen …

10. Epidemiologie von Staphylococcus aureus

11. Successful treatment of relapsing disseminated coccidioidomycosis with cutaneous involvement with posaconazole

    2008 - A 52-year-old woman with pulmonary sarcoidosis on immunosuppressive therapy developed pulmonary infiltrates and cutaneous granulomatous abscesses after a trip to the USA in April 2005. A hyphomycete …

12. Delineation of the recombination sites necessary for integration of pathogenicity islands II and III into the Escherichia coli 536 chromosome

    2008 - In uropathogenic Escherichia coli strain 536, six pathogenicity islands (PAIs) encode key virulence factors. All PAIs except PAI IV536 are flanked by direct repeats and four of them encode integrases …

13. Comparison of rubella seroepidemiology in 17 countries: progress towards international disease control targets

    2008 - Objective To standardize serological surveillance to compare rubella susceptibility in Australia and 16 European countries, and measure progress towards international disease-control targets. Methods …

14. Successful salvage treatment of disseminated cutaneous fusariosis with liposomal amphotericin B and terbinafine after allogeneic stem cell transplantation

    2008 - Fusarium infections are associated with high mortality after allogeneic stem cell transplantation. We report on successful treatment of a disseminated cutaneous Fusarium proliferatum infection using …

15. Extracting key information from historical data to quantify the transmission dynamics of smallpox

    2008 - Background Quantification of the transmission dynamics of smallpox is crucial for optimizing intervention strategies in the event of a bioterrorist attack. This article reviews basic methods and …

16. Vibrational Spectroscopy in Microbiology and Medical Diagnostics

17. Human Borna disease virus-infection and its therapy in affective disorders. [Review]

    2008 - Patients with affective disorders show an enhanced prevalence of Borna disease virus (BDV)-infection. Furthermore, BDV causes latent infection preferably in limbic central nervous structures and is …

18. Filoviruses: Interactions with the host cell

    2008 - The highly pathogenic filoviruses, Marburg and Ebola virus, are difficult to handle and knowledge of the interactions between filoviruses and their host cells remained enigmatic for many years. Two …

19. Lyme-Borreliose: Forschungsbedarf und Forschungsansätze. Ergebnisse eines interdisziplinären Expertentreffens am Robert Koch-Institut.

    2008 - Die Lyme-Borreliose ist in der nördlichen Hemisphäre nach aktuellem Kenntnisstand die häufigste durch Zecken übertragene Infektionskrankheit.  Deutschland ist neben anderen europäischen Ländern ein …

20. Signaling pathways induced by Influenza Virus

    2008 - Influenza viruses remain a continuous and severe global health threat to man as well as to many other mammals and birds. The re-emerging disease causes thousands of deaths and significant economic …

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