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1. GPS - Gute Praxis Sekundärdatenanalyse: Revision nach grundlegender Überarbeitung

   2008 - Die wissenschaftliche Nutzung von Sekundärdaten hat seit der Verabschiedung der Guten Praxis Sekundärdatenanalyse (GPS) im Jahr 2005 weiter zugenommen. Auf der Basis der Rückmeldungen auf diese …

2. Die Entwicklung des Bundesinstituts für Arzneimittel und Medizinprodukte (BfArM) im zunehmenden europäischen Wettbewerb.

   2008 - Das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) ist unter anderem verantwortlich für die Zulassung von wirksamen und unbedenklichen Arzneimitteln (AM) sowie für die Überwachung von …

3. Outcome of community-acquired pneumonia: influence of age, residence status and antimicrobial treatment

   2008 - Community-acquired pneumonia remains a major cause of mortality in developed countries. There is much discrepancy in the literature regarding factors influencing the outcome in the elderly population. …

4. Faecal shedding, alimentary clearance and intestinal spread of prions in hamsters fed with scrapie

   2008 - Shedding of prions via faeces may be involved in the transmission of contagious prion diseases. Here, we fed hamsters 10 mg of 263K scrapie brain homogenate and examined the faecal excretion of …

5. Report Versorgungsforschung

6. Ernährung

7. Surface-Enhanced Raman Scattering for Investigations of Eukaryotic Cells

8. Monitoring der gesundheitlichen Versorgung in Deutschland: Konzepte, Anforderungen, Datenquellen

9. Stimulus (polyphenol, IFN-γ, LPS)-dependent nitric oxide production and antileishmanial effects in RAW 264.7 macrophages

   2008 - The effects of interferon (IFN-γ), lipopolysaccharide (LPS), and some polyphenols as individual stimuli, as well as in various combinations on NO production in non-infected and infected …

10. Intracellular parasite kill:  Flow cytometry and NO detection for rapid discrimination between anti-leishmanial activity and macrophage activation

    2008 - Transgenic Leishmania expressing fluorescent reporter proteins such as green fluorescent protein (GFP) have opened the way for a flow cytometry (FACS)-based method to assess the killing of Leishmania …

11. Changes in protein structure and distribution observed at pre-clinical stages of scrapie pathogenesis

    2008 - Scrapie is a neurodegenerative disorder that involves the misfolding, aggregation and accumulation of the prion protein (PrP). The normal cellular PrP (PrPC) is rich in α-helical secondary structure, …

12. Mundhygiene. Daten des KiGGS zum Karies-präventiven Verhalten. [Oral hygiene. KIGGS data on caries preventative behaviour].

    2008 - Die vorliegende Analyse dient der Identifizierung von Risikogruppen bezüglich Mundhygiene und Kariesprävention bei Kindern und Jugendlichen in Deutschland. Im Kinder- und Jugendgesundheitssurvey …

13. Wie geht es unseren Kindern? Ergebnisse aus dem bundesweit repräsentativen Kinder- und Jugendgesundheitssurvey (KiGGS)

14. Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats

    2008 - Studies showed that the metabolic unlike the neuroendocrine effects of ghrelin could be abrogated by co-administered unacylated ghrelin. The aim was to investigate the interaction between ghrelin and …

15. Tabakrauchen und problematischer Alkoholkonsum unter Allgemeinkrankenhauspatienten

16. Smoking as a risk factor for thyroid volume progression and incident goiter in a region with improved iodine supply

    2008 - Objective: The role of smoking in the pathogenesis of thyroid enlargement is currently under debate. It has been hypothesized that the effect of smoking on increased thyroid volume is larger in …

17. Histoplasmosis in Europe: report on an epidemiological survey from the European Confederation of Medical Mycology Working Group

    2008 - The purpose of this survey was to systematically collect data on individuals with histoplasmosis in Europe over a 5-year period (from January 1995 to December 1999). This included information on where …

18. No evidence for PERV release by islet cells from German landrace pigs

19. Zum aktuellen Stand eines Gesundheitsmonitoringssystems am Robert Koch-Institut

20. Effectiveness of hexavalent vaccines against invasive Haemophilus influenzae type b disease: Germany’s experience after 5 years of licensure

    2008 - Vaccine effectiveness (VE) was determined with a case-cohort approach using Cox regression. Cases with confirmed systemic Hib infections in children born from 1 August 2000 to 31 December 2004 were …

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