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1. The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

   2010 - After being activated by antigen, helper T lymphocytes switch from a resting state to clonal expansion. This switch requires inactivation of the transcription factor Foxo1, a suppressor of …

2. Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation

   2010 - The overall prognosis of patients with advanced melanoma is poor due to the lack of effective treatment. A key factor for successful therapy is an early detection of disease. Therefore, reliably …

3. Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States

   2010 - Background XMRV, a xenotropic murine leukemia virus (MuLV)-related virus, was recently identified by PCR testing in 67% of persons with chronic fatigue syndrome (CFS) and in 3.7% of healthy persons …

4. A community-based survey of abdominal pain prevalence, characteristics, and health care use among children (vol 7, pg 1062, 2009). Correction

5. Body mass index percentiles for children and adolescents in Germany based on a nationally representative sample (KiGGS 2003-2006)

   2010 - Objective: To present body mass index (BMI) percentiles representative for children in Germany and to compare them with the currently used percentiles by Kromeyer–Hauschild (KH) and international …

6. Vaccine protection against lethal homologous and heterologous challenge using recombinant AAV vectors expressing codon-optimized genes from pandemic swine origin influenza virus (SOIV)

   2010 - The recent H1N1 influenza pandemic and the inevitable delay between identification of the virus and production of the specific vaccine have highlighted the urgent need for new generation influenza …

7. A 14-year-old girl with a vesicle on her finger and lymphadenitis

8. Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating antiretroviral therapy – the CASCADE collaboration: a collaboration of 23 cohort studies

   2010 - Background CD4 cell count is a strong predictor of the subsequent risk of AIDS or death in HIV-infected patients initiating combination antiretroviral therapy (cART). It is not known whether the rate …

9. Influence of household contacts on the effectiveness of face masks for preventing influenza in a healthcare setting: a comment on Cowling et al. (2010)

10. Resistance management in chronic hepatitis B complicated by renal failure

    2010 - Therapy of chronic hepatitis B has improved by the invention of the potent nucleos(t)ide analogues entecavir, telbivudine and tenofovir disoproxil. Due to increasing prevalence of lamivudine …

11. The mumps virus small hydrophobic protein targets ataxin-1 ubiquitin-like interacting protein (ubiquilin 4)

    2010 - The small hydrophobic (SH) protein of mumps virus has been reported to interfere with innate immunity by inhibiting TNF-alpha-mediated apoptosis. In a yeast two-hybrid screen we have identified the …

12. The Impact of Having a Loved One With Alcohol Consumption-Related Problems on Subjective Health Status and Health-Risk Behaviors in a General Hospital Sample

    2010 - Consecutively admitted inpatients of a general hospital in Northern Germany (N = 2903) completed a standardized screening questionnaire in 2005-2006 containing questions about alcohol …

13. Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference

    2010 - EUROPRISE is a Network of Excellence sponsored from 2007 to 2011 by the European Commission within the 6th Framework Program. The Network encompasses a wide portfolio of activities ranging from an …

14. Hepatitis B Virus Infections Among Children and Adolescents in Germany: Migration Background as a Risk Factor in a Low Seroprevalence Population

    2010 - BACKGROUND: Data on hepatitis B (HB) infection prevalence among children and adolescents in Germany are scarce. We estimated seroprevalence of HB infection and assessed determinants for HB infection …

15. Size and Mechanical Stability of Norovirus Capsids depend on pH - A Nanoindentation Study

    2010 - Norovirus - like particles (VLPs), were imaged with Atomic Force Microscopy. The mechanical stability of the VLPs was probed by nanoindentation at pH values ranging from 2 - 10. This range includes pH …

16. Evolutionary analysis and distribution of type III effector genes in pathogenic Escherichia coli from human, animal and food sources

    2010 - Molecular analysis of Shiga toxin-producing Escherichia coli (STEC) from different sources is considered as a major approach to assess their risk potential. However, only limited data are available …

17. Herausforderungen an die Gesundheitsforschung für eine alternde Gesellschaft am Beispiel „Multimorbidität“. [Challenges to health research for aging populations using the example of “multimorbidity”].

    2010 - Indem ein wachsender Anteil der Bevölkerung ein hohes Alter erreicht, ändern sich Krankheitsspektrum und Versorgungsbedarf. Besondere Herausforderungen für das Gesundheitssystem ergeben sich durch …

19. Differentiation between polymorphisms and resistance-associated mutations in human cytomegalovirus DNA polymerase

    2010 - Specific mutations in the human cytomegalovirus (HCMV) DNA polymerase (pUL54) are known to confer resistance against all currently licensed drugs for treatment of HCMV infection and disease. Following …

20. Preventing the pollution of mitochondrial datasets with nuclear mitochondrial paralogs (numts)

    2010 - Molecular tools have become prominent in ecology and evolution. A target of choice for molecular ecologists and evolutionists is mitochondrial DNA (mtDNA), whose many advantages have also convinced …

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