Search results
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Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract
2010 - Xenotropic murine leukemia virus–related gammaretrovirus (XMRV) has been recently associated with prostate cancer and chronic fatigue syndrome. To identify nucleic acid sequences, we examined …
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Alcohol dependent inpatients who receive general hospital care vs. detoxification in psychiatric care and alcohol problem 1 year later
2010 - Aim The aims were to investigate differences between alcohol dependent inpatients who seek alcohol treatment and those who do not seek alcohol specific but general hospital treatment, and to …
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HLA-B27 heavy chains distinguished by a micropolymorphism exhibit differential flexibility
2010 - Objective. Although the products of the human leukocyte antigen subtypes HLA-B*2705 and HLA-B*2709 differ only in residue 116 (Asp vs. His) within their peptide binding grooves, they are …
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Application of new assays for rapid confirmation and genotyping of isolates of Rubella virus
2010 - Rubella virus (RV) isolation is recommended by the WHO Measles and Rubella Labnet for studying the etiology and epidemiology of rubella. However, the absence of cytopathologic effects (CPE) in many of …
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Gesundheitliche Situation von Kindern alleinerziehender Mütter in Deutschland
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Variable genetic element typing: a quick method for epidemiological subtyping of Legionella pneumophila
2010 - A total of 57 isolates of Legionella pneumophila were randomly selected from the German National Legionella strain collection and typed by monoclonal antibody subgrouping, seven-gene locus …
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Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens
2010 - During the past 15 years, emergence and dissemination of β-lactam resistance in nosocomial Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii, became a serious problem worldwide. …
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Peripherally injected CCK-8S activates CART positive neurons of the paraventricular nucleus in rats
2010 - Cholecystokinin (CCK) plays a role in the short-term inhibition of food intake. Cocaine- and amphetamine-regulated transcript (CART) peptide has been observed in neurons of the paraventricular nucleus …
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Two siblings with immunodeficiency, facial abnormalities and chromosomal instability without mutation in DNMT3B gene but liability towards malignancy; a new chromatin disorder delineation?
2010 - Background ICF syndrome (standing for Immunodeficiency, Centromere instability and Facial anomalies syndrome) is a very rare autosomal recessive immune disorder caused by mutations of the gene de novo …
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Mutation pattern of lamivudine resistance in relation to hepatitis B genotypes: hepatitis B genotypes differ in their lamivudine resistance associated mutation pattern
2010 - Little is known about differences between individual hepatitis B genotypes and mutation patterns associated with lamivudine resistance. This study analyses the lamivudine-associated mutation pattern …
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Spotlight on measles 2010: Measles outbreak among travellers returning from a mass gathering, Germany, September to October 2010
2010 - In September and October 2010, 13 primary measles cases were identified among unvaccinated persons aged between 9 and 32 years (median: 16.5) in 11 districts in Germany. All cases had attended …
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Microtubes self-assembled from a cholesterol-modified nucleoside
2010 - We describe the formation of lipid microtubes from a novel cholesterol-modified nucleoside in binary mixture with phospholipids. Stable cylindrical structures with an outer diameter of 2-3 microm and …
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Antiretroviral activity of two polyisoprenylated acylphloroglucinols, 7-epi-nemorosone and plukenetione A, isolated from Caribbean propolis
2010 - Objectives: Polyisoprenylated acylphloroglucinols have recently emerged as antitumoral agents. This study aims at elucidating the antiretroviral activity of two such compounds which were isolated from …
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Severe H1N1 infection in a pediatric liver transplant recipient treated with intravenous zanamivir: efficiency and complications
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Tsg101 Is Recruited by a Late Domain of the Nucleocapsid Protein To Support Budding of Marburg Virus-Like Particles
2010 - The nucleoprotein NP of Marburg virus (MARV) is the major component of the viral nucleocapsid, which also consists of the viral proteins VP35, L, and VP30, as well as the viral genome. During virus …
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SIVagm containing the SHIV89.6P Envelope gene replicates poorly and is non-pathogenic
2010 - SIVagm does not induce disease in its African green monkey (AGM) host. In comparison, the hybrid simian-human immunodeficiency virus SHIV89.6P that carries the HIV env gene induces disease in rhesus …
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Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: The role of the C-terminal ESEV motif in the viral NS1 protein
2010 - We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A virus. The NS1 proteins of most …
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First report of a Cryptococcus magnus infection in a cat
2010 - This report describes an uncommon case of cryptococcosis in an apparently immunocompetent cat caused by Cryptococcus magnus. An amputation of the complete left foreleg and excision of the ipsilateral …
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Fluoroquinolone resistance and Clostridium difficile, Germany
2010 - We characterized 670 Clostridium difficile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of …
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Clinical Outcome of HIV-Infected Patients with Discordant Virological and Immunological Response to Antiretroviral Therapy
2010 - Background. A subgroup of human immunodeficiency virus type 1 (HIV-1)–infected patients with severe immunodeficiency show persistently low CD4+ cell counts despite sustained viral suppression. It is …
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