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1. Temporal changes in the gene signatures of BCG-vaccinated guinea pigs in response to different mycobacterial antigens.

   2010 - Mycobacterium bovisBCG-vaccination in the guinea pig model of tuberculosis (TB) is sufficiently protective that candidate TB vaccines are judged against this. Little is understood about how the BCG …

2. Physical inactivity and cognitive performance after 2.5 year follow up: Results from the Survey of Health, Ageing and Retirement (SHARE)

   2010 - Objective: To examine the association between physical activity and cognitive performance in a longitudinal study. Methods: We analyzed data from 17.333 noninstitutionalized persons aged 50 years or …

3. Depression in middle-aged and older first generation migrants in Europe: Results from the Survey of Health, Ageing and Retirement in Europe (SHARE)

   2010 - OBJECTIVE: To determine the prevalence of depression in migrants aged 50 years or older in comparison to residents without a history of migration in 11 European countries. METHODS AND SUBJECTS: The …

4. Treatment of cancer with antibodies to costimulating polypeptide of T cells

   2010 - A polypeptide (8F4 molecule) with a T-cell costimulating biological activity is disclosed, as well as monoclonal antibodies against the 8F4 molecule and hybridoma cells which produce the monoclonal …

5. Das Gesundheitsmonitoring am Robert Koch-Institut – Nicht nur Infektionskrankheiten zeigen Dynamik

6. Unusual presentation of Trichophyton verrucosum causing hydronephrosis and joint contractures

7. A Novel Highly Reproducible and Lethal Nonhuman Primate Model for Orthopox Virus Infection

   2010 - The intentional re-introduction of Variola virus (VARV), the agent of smallpox, into the human population is of great concern due it's bio-terroristic potential. Moreover, zoonotic infections with …

8. Tick-borne encephalitis: from childhood to golden age does increased mobility mean increased risk? Conference report of the 11th meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE)

9. Epidemiology of severe Clostridium difficile infections in Hesse, Germany in 2008-2009

   2010 - Zusammenfassung Hintergrund und Fragestellung: Clostridium difficile ist ein weit verbreitetes Bakterium, das als Erreger von nosokomialen Infektionen zunehmend an Bedeutung gewinnt. Seit 2000 nehmen …

10. High prevalence of porcine Hokovirus in German wild boar populations

    2010 - Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing …

11. Characteristics and outcome of 27 elbow periprosthetic joint infection: Results from a 14-year cohort study of 358 elbow prostheses

    2010 - Elbow arthroplasty is increasingly performed in patients with rheumatic and post-traumatic arthritis. Data on elbow periprosthetic joint infection (PJI) are limited. We investigated the …

12. Population prevalence of obstructive sleep apnoea in a community of German third graders

    2010 - We aimed to estimate the population prevalence of obstructive sleep apnoea (OSA) in an urban community of German third graders and the diagnostic test accuracy of two OSA screening methods. Using a …

13. Spotlight on measles 2010: measles outbreak in a mainly unvaccinated community in Essen, Germany, March-June 2010

    2010 - On 15 March 2010, a case of measles was reported to the District Health Office in Essen. In total 71 cases occurred from 15 March to 19 May (four cases hospitalised), with the majority linked to a …

14. Epidemiology of reported Yersinia enterocolitica infections in Germany, 2001-2008

    2010 - Background Yersiniosis is the third most common zoonotic bacterial disease in Germany and the European Union. Sequelae of Yersinia enterocolitica infections, such as reactive arthritis, have been …

15. Differences in carotid plaque content of macrophages, T cells and MMP-9 between patients with embolic and hemodynamic cerebral ischemia due to symptomatic carotid stenosis

    2010 - Background Cerebral ischemia in patients with carotid artery atherosclerosis is most often caused by thromboembolism, while hemodynamic stroke mechanism is rare. Differences in plaque inflammation …

16. Sozioökonomische Faktoren und Verbreitung von Adipositas

    2010 - Hintergrund: Aus verschiedenen Studien ist bekannt, dass die Verbreitung von Adipositas einem sozialen Gradienten folgt. Untersucht wird, welche relative Bedeutung den Statusindikatoren Einkommen, …

17. Characterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C

    2010 - BACKGROUND: Porcine endogenous retroviruses (PERVs) pose a potential risk for xenotransplantation using pig cells, tissues or organs. A special threat comes from viruses generated by recombination …

18. Beneficial and detrimental effects of human endogenous retroviruses

    2010 - In this mini review, we aim to evaluate the structure and function of Human Endogenous Retroviruses (HERVs) with respect to the benefit they may have for humans or the damage they may cause. Emphasis …

19. Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

    2010 - Influenza A virus, being responsible for seasonal epidemics and reoccurring pandemics, represents a worldwide threat to public health. High mutation rates facilitate the generation of viral escape …

20. Methicillin-resistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe

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