Search results
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Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study
2011 - Background The effect of transmitted drug resistance (TDR) on first-line combination antiretroviral therapy (cART) for HIV-1 needs further study to inform choice of optimum drug regimens. We …
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Dengue in Thailand and Cambodia: An Assessment of the Degree of Underrecognized Disease Burden Based on Reported Cases
2011 - Background Disease incidence data are needed to guide decision-making for public health interventions. Although dengue is a reportable disease in Thailand and Cambodia, the degree that reported …
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Host range of enterococcal vanA plasmids among Gram-positive, intestinal bacteria
2011 - Objectives The most prevalent type of acquired glycopeptide resistance is encoded by the vanA transposon Tn1546 located mainly on transferable plasmids in Enterococcus faecium. The limited occurrence …
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Monitoring pandemic influenza A(H1N1) vaccination coverage in Germany 2009/10 - Results from thirteen consecutive cross-sectional surveys
2011 - To monitor pandemic influenza A(H1N1) vaccine uptake during the vaccination campaign in Germany 2009/10, thirteen consecutive cross-sectional telephone-surveys were performed between November 2009 and …
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Hepatitis E - Häufiger eine autochthone als eine importierte Erkrankung
2011 - Hepatitis E ist eine seltene, seit 2001 in Deutschland meldepflichtige Erkrankung. Seither wurden jedes Jahr zwischen 11 und 62 importierte Hepatitis-E-Virus-(HEV) Infektionen übermittelt. Von diesen …
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Watch out for the even eviler cousin – sorbitol-fermenting E. coli O157
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Enhanced surveillance during a large outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany, May to June 2011
2011 - Germany has a well established broad statutory surveillance system for infectious diseases. In the context of the current outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga …
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The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia
2011 - Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and sepsis. Pneumococci can be divided into >90 serotypes that show differences in the pathogenicity and invasiveness. We tested …
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BMI-Selbstauskünfte – Überprüfung der Praktikabilität einer Korrekturformel an einer Stichprobe elf- bis 13-jähriger Mädchen. [Self-assessment of BMI data. Verification of the practicability of a correction formula on a sample of 11- to 13-year-old girls].
2011 - Die Entscheidung zwischen Messung und Erfragung von Größe und Gewicht zur Errechnung des Body-Mass-Index (BMI) hat Einfluss auf die Ökonomie und Validität dieser Messungen. So sind Selbstauskünfte …
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Standardization of hepatitis E virus (HEV) nucleic acid amplification technique-based assays: an initial study to evaluate a panel of HEV strains and investigate laboratory performance
2011 - The performance of hepatitis E virus (HEV) RNA nucleic acid amplification (NAT)-based assays has been investigated using a panel of HEV-containing plasma samples. The panel comprised 22 HEV-positive …
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Present state and future perspectives of using pluripotent stem cells in toxicology research
2011 - The use of novel drugs and chemicals requires reliable data on their potential toxic effects on humans. Current test systems are mainly based on animals or in vitro-cultured animal-derived cells and …
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Functional dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica
2011 - Salmonella enterica deploys the giant non-fimbrial adhesin SiiE to adhere to the apical side of polarized epithelial cells. The establishment of close contact is a prerequisite for subsequent invasion …
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Comparison of Staphylococcus aureus isolates associated with food intoxication with isolates from human nasal carriers and human infections
2011 - Staphylococcus aureus represents an organism of striking versatility. While asymptomatic nasal colonization is widespread, it can also cause serious infections, toxinoses and life-threatening …
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Comparison of direct cultivation on a selective solid medium, polymerase chain reaction from an enrichment broth, and the BD GeneOhm™ VanR Assay for identification of vancomycin-resistant enterococci in screening specimens
2011 - Fast and reliable diagnostics of vancomycin-resistant enterococci (VRE) is an important prerequisite for containing VRE transmission rates and controlling VRE outbreaks among hospital patients. The BD …
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Peginterferon plus adefovir versus either drug alone for hepatitis delta
2011 - BACKGROUND: Chronic infection with hepatitis B virus and hepatitis delta virus (HDV) results in the most severe form of viral hepatitis. There is no currently approved treatment. We investigated the …
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Epidemiologie der Tuberkulose – Aktuelle Situation in Deutschland und weltweit
2011 - Auch im 21. Jahrhundert gehört die Tuberkulose (TB) noch zu den weltweit häufigsten Infektionskrankheiten. Nach den Schätzungen der Weltgesundheitsorganisation (WHO) erkrankten im Jahr 2008 mehr als …
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Rotavirus genotypes co-circulating in Europe between 2006 and 2009 as determined by EuroRotaNet, a pan-European collaborative strain surveillance network
2011 - EuroRotaNet, a laboratory network, was established in order to determine the diversity of co-circulating rotavirus strains in Europe over three or more rotavirus seasons from 2006/2007 and currently …
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Hepatitis B Virus Infections Among Children and Adolescents in Germany: Migration Background as a Risk Factor in a Low Seroprevalence Population
2011 - Background: Data on hepatitis B (HB) infection prevalence among children and adolescents in Germany are scarce. We estimated seroprevalence of HB infection and assessed determinants for HB infection …
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Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007
2011 - Objectives To investigate the genetic environment of the metallo-β-lactamase gene blaNDM-1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods Antimicrobial susceptibility …
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Transactivation of human parvovirus B19 gene expression in endothelial cells by adenoviral helper functions
2011 - Human parvovirus B19 (B19V) DNA is highly prevalent in endothelial cells lining up intramyocardial arterioles and postcapillary venules of patients with chronic myocarditis and cardiomyopathies. We …
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