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Epidemiology of Rotavirus Infections in Children <5 Years of Age: Germany, 2001-2008
2011 - BACKGROUND: Rotavirus (RV) infection is the leading cause of acute gastroenteritis in young children worldwide. In 2006, 2 live-attenuated RV-vaccines became available for use in infants </=6 months …
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A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages
2011 - Parasitic worms alter their host's immune system to diminish the inflammatory responses directed against them, using very efficient immunomodulating molecules. We have previously shown that the …
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Orlistat: A repositioning opportunity as a growth inhibitor of Apicomplexan parasites?
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Avian influenza virus risk assessment in falconry
2011 - Background There is a continuing threat of human infections with avian influenza viruses (AIV). In this regard falconers might be a potential risk group because they have close contact to their …
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Development of sensitive methods for detection of porcine endogenous retrovirus-C (PERV-C) in the genome of pigs
2011 - Porcine endogenous retroviruses (PERV) represent a risk for xenotransplantation using pig cells, tissues or organs. PERV-A and PERV-B are present in the genome of all pigs and both infect human cells …
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Detection of human-pathogenic poxviruses
2011 - With the eradication of smallpox about 30 years ago, the identification and differentiation of other poxviruses with varying pathogenicity in humans present a challenge for diagnostic facilities. …
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Highly sensitive detection of the group A Rotavirus using Apolipoprotein H-coated ELISA plates compared to quantitative real-time PCR
2011 - Background The principle of a capture ELISA is binding of specific capture antibodies (polyclonal or monoclonal) to the surface of a suitable 96 well plate. These immobilized antibodies are capable of …
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Preventing the next 'SARS' - European healthcare workers' attitudes towards monitoring their health for the surveillance of newly emerging infections: qualitative study
2011 - Background Hospitals are often the epicentres of newly circulating infections. Healthcare workers (HCWs) are at high risk of acquiring infectious diseases and may be among the first to contract …
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The proof of the pudding is in the eating: an outbreak of emetic syndrome after a kindergarten excursion, Berlin, Germany, December 2007
2011 - An outbreak of food poisoning (emetic syndrome) occurred in three kindergartens (A, B and C) in Berlin, Germany, on 3 December 2007 after an excursion during which food was served. We conducted a …
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Herpes zoster in Germany: Quantifying the burden of disease
2011 - BACKGROUND: Herpes zoster (HZ) is caused by a reactivation of the varicella-zoster-virus (VZV) and mainly affects individuals aged ≥ 50 years. Vaccines have been licensed or are under development that …
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Recognition of Clostridium difficile PCR-ribotypes 001, 027 and 126/078 using an extended MALDI-TOF MS system
2011 - During the last decade, Clostridium difficile infection (CDI) increased markedly inside as well as outside of hospitals. In association with the occurrence of new hypervirulent C. difficile strains, …
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Emergence of β-lactamases OXA-10, VEB-1 and CMY in Providencia spp. from Nigeria
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Surveillance trends of the 2009 influenza A(H1N1) pandemic in Europe
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Reply letter. To Miller N. Comment on "Forecasting dengue vaccine demand in disease endemic and non-endemic countries" Amarasinghe et al; Hum Vaccines 2010; 6:9, 745-753
2011 - We acknowledge the comments by N. Miller on our estimates of the potential dengue vaccine demand among international travelers. We agree that the number of travelers in 2015-20 would be the …
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Absence of infection in pigs inoculated with high-titre recombinant PERV-A/C
2011 - Porcine endogenous retroviruses (PERVs) represent a risk for xenotransplantation using pig cells or organs since they are integrated in the genome of all pigs and infect human cells in vitro. …
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Pyrosequencing allows the detection of emergent ganciclovir resistance muations after HCMV infection
2011 - Prenatally acquired human cytomegalovirus (HCMV) infection is the most frequent viral infection of newborns in developed countries. Virostatic therapy is accompanied by side effects and stepwise …
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Factors affecting patterns of tick parasitism on forest rodents in tick-borne encephalitis risk areas, Germany
2011 - Identifying factors affecting individual vector burdens is essential for understanding infectious disease systems. Drawing upon data of a rodent monitoring programme conducted in nine different forest …
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Determinants of tick-borne encephalitis virus antibody presence in roe deer (Capreolus capreolus) sera
2011 - In order to identify variables associated with the presence of the tick-borne encephalitis (TBE) virus, we conducted a serological survey of roe deer [Capreolus capreolus (Artiodactyla: Cervidae, …
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Revealing new transmission routes of measles virus using sequence analysis of phosphoprotein- and haemagglutinin genes
2011 - With improved measles virus (MV) control, the genetic variability of MV-nucleoprotein hypervariable region (NP-HVR) decreases. Thus it becomes increasingly difficult to determine the origin of a virus …
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Human endogenous retrovirus K (HERV-K) is expressed in villous and extravillous cytotrophoblast cells of the human placenta
2011 - Human endogenous retroviruses (HERVs) have been shown to be important in physiological and pathophysiological processes in humans. Several HERVs have been found to be expressed in the placenta—a …
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