Search results
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Berlin Symposium on Xenotransplantation, June 9–10, 2011
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Mitochondrial lipoic acid scavenging is essential for Plasmodium berghei liver stage development
2012 - Lipoic acid is an essential cofactor for enzymes that participate in key metabolic pathways in most organisms. While in mammalian cells lipoylated proteins reside exclusively in the mitochondria, …
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Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells
2012 - Chlamydophila pneumoniae causes acute respiratory tract infections and has been associated with development of asthma and atherosclerosis. The production of IL-1β, a key mediator of acute and chronic …
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High frequency of Tropheryma whipplei in culture-negative endocarditis
2012 - “Classical” Whipple’s disease (cWD) is caused by Tropheryma whipplei and is characterized by arthropathy, weight loss, and diarrhea. T. whipplei infectious endocarditis (TWIE) is rarely reported, …
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Features of ‘All LNA’ duplexes showing a new type of nucleic acid geometry
2012 - ‘Locked nucleic acids’ (LNAs) belong to the backbone-modified nucleic acid family. The 2'- O,4'-C-methylene-β-D-ribofuranose nucleotides are used for single or multiple substitutions in RNA molecules …
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Überblick über primärpräventive Maßnahmen zur Förderung von körperlicher Aktivität in Deutschland. [Overview of primary prevention measures to promote physical activity in Germany].
2012 - Der vorliegende Beitrag gibt einen Überblick über primärpräventive Maßnahmen zur Förderung der körperlichen Aktivität in Deutschland. Zuerst werden die gesundheitsrelevanten Empfehlungen für …
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Chronic wasting disease: Fingerprinting the culprit in risk assessments
2012 - Transmissible spongiform encephalopathies (prion diseases) in animals may be associated with a zoonotic risk potential for humans as shown by the occurrence of variant Creutzfeldt-Jakob disease in the …
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Epidemiologische Forschung zu allergischen Erkrankungen in Deutschland: Eine Chronologie
2012 - Epidemiological research on allergic disease in Germany: A chronology Asthma and allergies are important chronic diseases. Epidemiological studies can aid the understanding of incidence, distribution, …
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Prenatal allergen exposures prevent allergen-induced sensitization and airway inflammation in young mice
2012 - Background: Immune-modulation such as tolerance induction appears to be an upcoming concept to prevent development of atopic diseases. Pregnancy might present a critical period for preventing allergic …
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Low-carbon acclimation in carboxysome-less and photorespiratory mutants of the cyanobacterium Synechocystis sp. strain PCC 6803
2012 - Using metabolic and transcriptomic phenotyping, we studied acclimation of cyanobacteria to low-carbon (LC) conditions and the requirements for coordinated alteration of metabolism and gene expression. …
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International differences in self-reported health measures in 33 major metropolitan areas in Europe
2012 - Background: The increasing concentration of populations into large conurbations in recent decades has not been matched by international health assessments, which remain largely focused at the country …
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Emergence of Minor Drug-Resistant HIV-1 Variants after Triple Antiretroviral Prophylaxis for Prevention of Vertical HIV-1 Transmission
2012 - Background WHO-guidelines for prevention of mother-to-child transmission of HIV-1 in resource-limited settings recommend complex maternal antiretroviral prophylaxis comprising antenatal zidovudine …
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DivIVA affects secretion of virulence-related autolysins in Listeria monocytogenes
2012 - DivIVA is a well conserved coiled-coil protein present in most Gram positive bacteria and has been implicated in division site selection, peptidoglycan biosynthesis, and sporulation. DivIVA proteins …
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Unterschiede bei Gesundheitsrisiken, Morbidität und gesundheitlicher Versorgung zwischen Kindern GKV- bzw. PKV-versicherter Eltern: Ergebnisse aus dem Kinder- und Jugendgesundheitssurvey (KiGGS)
2012 - Hintergrund: Die wenigen Studien zum Vergleich zwischen GKV- und PKV-versicherten Erwachsenen zeigen, dass die GKV-Versicherten zumeist kränker sind und öfter zu einem Allgemeinarzt gehen. Die …
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Survival from common and rare cancers in Germany in the early 21st century
2012 - Background: Until recently, population-based data of cancer survival in Germany mostly relied on one registry covering 1 million people (1.3% of the German population). Here, we provide up-to-date …
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Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury
2012 - Programmed cell death is a crucial cellular response frequently observed in IV-infected tissue. This article reviews the current knowledge on the molecular virus–host interactions that induce …
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Determinants of tick-borne encephalitis virus antibody presence in roe deer (Capreolus capreolus) sera
2012 - In order to identify variables associated with the presence of the tick-borne encephalitis (TBE) virus, we conducted a serological survey of roe deer [Capreolus capreolus (Artiodactyla: Cervidae, …
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Uptake of Combination Antiretroviral Therapy (cART) and HIV Disease Progression According to Geographical Origin in Seroconverters in Europe, Canada, and Australia
2012 - Background. We examined differences by geographical origin (GO) in time from HIV seroconversion (SC) to AIDS, death, and initiation of antiretroviral therapy (cART). Methods. Data from HIV …
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Highly controlled electrofusion of individually selected cells in dielectrophoretic field cages
2012 - The prospect of novel therapeutic approaches has renewed the current interest in the fusion of rare cells, like stem cells or primary immune cells. While conventional techniques are only capable of …
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Comparative hepatitis A seroepidemiology in 10 European countries
2012 - The WHO recommends hepatitis A virus (HAV) immunization according to level of transmission and disease burden. We aimed to identify susceptible age groups by standardized serosurveys to inform HAV …
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