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1. Comparison of real-time PCR and MassTag PCR for the multiplex detection of highly pathogenic agents

   2012 - Multiplex PCR assays are a cost- as well as labour-effective way to analyse one sample for several pathogens simultaneously. Besides the mutual competition of the individual PCR reactions included in …

2. Gesundheitliche Ungleichheit im Jugendalter - Welche Bedeutung kommt der Schulbildung zu?

3. Comparison of Staphylococcus aureus isolates associated with food intoxication with isolates from human nasal carriers and human infections

   2012 - Staphylococcus aureus represents an organism of striking versatility. While asymptomatic nasal colonization is widespread, it can also cause serious infections, toxinoses and life-threatening …

4. Multimorbidität als Interventionsherausforderung

5. Cowpox virus but not Vaccinia virus induces secretion of CXCL1, IL-8 and IL-6 and chemotaxis of monocytes in vitro

   2012 - Orthopoxviruses are large DNA viruses which can cause disease in numerous host species. Today, after eradication of Variola virus and the end of vaccination against smallpox, zoonotic Orthopoxvirus …

6. Viral evolution in chronic hepatitis B: a branched way to HBeAg seroconversion and disease progression?

7. Comparison of Shedding Characteristics of Seasonal Influenza Virus (Sub)Types and Influenza A(H1N1)pdm09; Germany, 2007–2011

   2012 - Background Influenza viral shedding studies provide fundamental information for preventive strategies and modelling exercises. We conducted a prospective household study to investigate viral shedding …

8. The role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction.

   2012 - Background Mycobacterium tuberculosis differs from most pathogens in its ability to multiply inside monocytes and to persist during long periods of time within granuloma in a status of latency. A …

9. Tissue Diagnosis of Invasive Fungal Infections: Current Limitations and the Emerging Use of Molecular Techniques

   2012 - Invasive fungal diseases (IFD) due to opportunistic fungi are commonly treated using empirical antifungal therapy. Therefore, a comprehensive study of organisms associated with IFD is essential to …

10. Clonal Dissemination of Salmonella enterica Serovar Infantis in Germany

    2012 - Salmonella enterica serovar Infantis (Salmonella Infantis) is consistently isolated from broiler chickens, pigs, and humans worldwide. This study investigated 93 epidemiologically unrelated Salmonella …

11. Induction of Antibodies Specific for Gp41 of HIV-1 by Gene Gun DNA Vaccination

    2012 - All attempts to induce broadly neutralising antibodies such as mAb 2F5 and mAb 4E10 targeting conserved epitopes in the membrane proximal external region (MPER) of the transmembrane envelope (TM) …

12. 120 years of koala retrovirus evolution determined from museum skins

    2012 - Although endogenous retroviruses are common across vertebrate genomes, the koala retrovirus (KoRV) is the only retrovirus known to be currently invading the germ line of its host. KoRV is believed to …

13. Association of Breastfeeding and Exposure to Maternal Smoking During Pregnancy with Children’s General Health Status Later in Childhood

    2012 - Background: Maternal smoking during pregnancy is associated with a variety of risks on fetal health, whereas breastfeeding may protect infants from infections in the early postpartum period. Little …

14. EHEC O104:H4 in Germany 2011: Large Outbreak of Bloody Diarrhea and Haemolytic Uraemic Syndrome by Shiga-Toxin-Producing E. coli via Contaminated Food

15. Hepatitis E Virus Seroprevalence among Adults, Germany

    2012 - We assessed hepatitis E virus (HEV) antibody seroprevalence in a sample of the adult population in Germany. Overall HEV IgG prevalence was 16.8% (95% CI 15.6%–17.9%) and increased with age, leveling …

16. Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis

    2012 - Background Ficolin-2 coded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity. In this study, we analyzed five functional polymorphisms of the FCN2 gene for their …

17. Deregulated MYC expression induces dependence upon AMPK-related kinase 5

    2012 - Deregulated expression of the MYC oncoprotein contributes to the genesis of many human tumours, yet strategies to exploit this for a rational tumour therapy are scarce. MYC promotes cell growth and …

18. Kultursensible HIV/STI-Prävention bei Sexarbeiterinnen mit Migrationshintergrund

    2012 - Hintergrund. Frauen, die migrieren und in der Sexarbeit arbeiten, haben ein erhöhtes Risiko, sich mit STI oder HIV zu infizieren. Im Rahmen einer Expertenbefragung wurden Aspekte kultursensibler …

19. Improved identification including MALDI-TOF mass spectrometry analysis of group D streptococci from bovine mastitis and subsequent molecular characterization of corresponding Enterococcus faecalis and Enterococcus faecium isolates

    2012 - We examined 199 group D streptococci isolated from clinically defined and epidemiologically unrelated cases of bovine mastitis. Samples were collected during a 5-month period from 2010 to 2011 from …

20. Second external quality assurance study for the serological diagnosis of hantaviruses in Europe

    2012 - Hantaviruses are endemic throughout the world and hosted by rodents and insectivores. Two human zoonoses, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), are …

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