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1. Seropositivity of Lyme Borreliosis and Associated Risk Factors: A Population-Based Study in Children and Adolescents in Germany (KiGGS)

   2012 - Background Lyme borreliosis (LB) caused by spirochetes of the Borrelia burgdorferi sensu lato complex is the most common tick-borne disease in the northern hemisphere. Data on the distribution and on …

2. Performance of three chromogenic VRE screening agars, two Etest® vancomycin protocols, and different microdilution methods in detecting vanB genotype Enterococcus faecium with varying vancomycin MICs

   2012 - Frequencies of vanB-type Enterococcus faecium increased in Europe during the last years. VanB enterococci show various levels of vancomycin MICs even below the susceptible breakpoint challenging a …

3. The role of XCR1 and its ligand XCL1 in antigen cross-presentation by murine and human dendritic cells

   2012 - Recently, the chemokine receptor XCR1 has been found to be exclusively expressed on a subset of dendritic cell (DC) known to be involved in antigen cross-presentation. This review aims to summarize …

4. Aufbereitung von Medizinprodukten

5. Prävention nosokomialer Infektionen – rechtliche Verankerung und nationale Standards

6. Cross-transmission rates of enterococcal isolates among newborns in a neonatal intensive care unit

   2012 - Enterococci are important pathogens causing nosocomial infections and patients at risk include also premature babies requiring intensive care treatment. Our aim was to assess occurrence and cross …

7. Rat hepatitis E virus: Geographical clustering within Germany and serological detection in wild Norway rats (Rattus norvegicus)

   2012 - Zoonotic hepatitis E virus (HEV) infection in industrialized countries is thought to be caused by transmission from wild boar, domestic pig and deer as reservoir hosts. The detection of HEV-specific …

8. Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo

   2012 - Background The rate of microscopic incomplete resections of gastrointestinal cancers including pancreatic cancer has not changed considerably over the past years. Future intra-operative applications …

9. National Health Data from the Robert Koch Institute

10. Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution

    2012 - Fossils and molecular data are two independent sources of information that should in principle provide consistent inferences of when evolutionary lineages diverged. Here we use an alternative approach …

11. Monitoring für Prävention und Gesundheitsförderung. Der Beitrag des Monitorings und seiner Berichterstattungssysteme zu Prävention und Gesundheitsförderung

    2012 - Hintergrund. Das Monitoring erhebt kontinuierlich Daten auf Bevölkerungsebene, die die Bedarfsermittlung und den Wirkungsnachweis von Maßnahmen der Prävention und Gesundheitsförderung unterstützen. Je …

12. Forschung mit humanen embryonalen Stammzellen in Deutschland

    2012 - Pluripotente Stammzellen des Menschen, deren Prototyp die humanen embryonalen Stammzellen (hES-Zellen) sind, stehen seit nunmehr fast 15 Jahren im Fokus des wissenschaftlichen Interesses. Mit dem …

13. Blood pressure and lipid management fall far short in persons with type 2 diabetes: Results from the DIAB-CORE Consortium including six German population-based studies

    2012 - Background Although most deaths among patients with type 2 diabetes (T2D) are attributable to cardiovascular disease, modifiable cardiovascular risk factors appear to be inadequately treated in …

14. Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid: cholesterol acyltransferase

    2012 - Background: PlaC is a GDSL enzyme and the major GCAT secreted by Legionella pneumophila. Results: The zinc metalloproteinase ProA processes and activates PlaC. Deletion of regions within a disulfide …

15. Datenqualität oder Unterschiede in der onkologischen Versorgung? – Berichtsstandards für Überlebenszeitanalysen mit Krebsregisterdaten. Ein Vorschlag der Gesellschaft der epidemiologischen Krebsregister in Deutschland e. V.

    2012 - Hintergrund: Die Ergebnisse bevölkerungsbasierter Überlebenszeitanalysen von Krebspatienten sind zentrale Bewertungskriterien für die onkologische Versorgung. Ihre Nutzung und Interpretation als …

16. Despite triple vaccination.

17. Detection of retroviral super-infection from non-invasive samples

    2012 - While much attention has been focused on the molecular epidemiology of retroviruses in wild primate populations, the correlated question of the frequency and nature of super-infection events, i.e., …

18. Auswirkungen von Nintendo-Wii® Bowling auf Altenheimbewohner

    2012 - Die wenigen Studien, die sich mit positiven Wirkungen auf den Gesundheitszustand und das Wohlbefinden älterer Menschen befassen, sind oft nur sehr einseitig ausgelegt. Ziel der vorliegenden Studie war …

19. CD4+ T Cells Rely on a Cytokine Gradient to Control Intracellular Pathogens beyond Sites of Antigen Presentation

    2012 - Effector T cells are critical for clearance of pathogens from sites of infection. Like cytotoxic CD8+ T cells, CD4+ helper T cells have been shown to deliver effector molecules directionally toward …

20. Immunodetection of inactivated Francisella tularensis bacteria by using a quartz crystal microbalance with dissipation monitoring

    2012 - Francisella tularensis are very small, gram-negative bacteria which are capable of infecting a number of mammals. As a highly pathogenic species, it is a potential bioterrorism agent. In this work we …

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